A.P. Bio poster

TV series

A.P. Bio

2018TV-144 seasons6.9 / 10

If he's taught them one thing, he's taught them too much.

When disgraced Harvard philosophy scholar Jack Griffin loses out on his dream job, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement biology teacher.

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Streaming, rental and purchase options

Where to watch in United States

Checked Jul 22, 2026

A.P. Bio is available to stream on Peacock and Peacock Premium in United States. You can also buy it from Amazon, Apple TV, and Fandango at Home. Use the direct links below to open the provider.

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Synopsis

When disgraced Harvard philosophy scholar Jack Griffin loses out on his dream job, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement biology teacher.

Cast, crew and production details

About A.P. Bio

Watch trailerA.P. Bio (NBC) Trailer HD - Glenn Howerton, Patton Oswalt comedy series

Cast

Glenn HowertonJack Griffin

Patton OswaltPrincipal Ralph Durbin

Paula PellHelen Henry Demarcus

Lyric LewisStef

Mary SohnMary

Jean VillepiqueMichelle

Tom BennettMiles

Tucker AlbrizziColin

Credits

Created by: Michael Patrick O'Brien
Written by: Michael Patrick O'Brien, Shelly Gossman, Donick Cary, Rob Klein, Charlie McCrackin, Emily Cutler, John Blickstead, Trey Kollmer, John Solomon, Luvh Rakhe

Production details

Status: Canceled
Series type: Scripted
Episodes: 42
Original language: English

Networks & production

NBCUnited States
PeacockUnited States
Broadway VideoUnited States
Sethmaker Shoemeyers ProductionsUnited States
Human Rabbit
Universal TelevisionUnited States

Themes

biology teacherclassroomhigh schoolhigh school teacherhilariousplayfulrevengesitcom

Season 2 episodes

Watch options above are for the show and may vary by season or episode.

← Season 1Season 3 →

Episode 1

Happiness

Mar 7, 201922m7.0 / 10

With no archrival to combat, Jack sets his sights on a new mission: write the most brilliant philosophy book ever and get out of Toledo for good. Stef and Mary forget a special day for Michele. Helen forgets to order routine maintenance for the copier causing mass hysteria at Whitlock.

Directed by Trent O'DonnellWritten by Donick CaryGuest stars Aparna Brielle, Sari Arambulo, John Pirruccello, Hans Holsen, Clint Culp, Freedom Bridgewater, Aiesha Eser, Allisyn Snyder

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Episode 2

Nuns

Mar 14, 201922m7.5 / 10

As the newly minted driver's education teacher, Jack sets out to get revenge on his mother's church when he discovers the last of her money was used to buy a statue of the Virgin Mary.

Directed by Lynn SheltonWritten by John Blickstead, Trey KollmerGuest stars Aparna Brielle, Sari Arambulo, Meagen Fay, Nancy Friedrich, Dan Gilvary, Allisyn Snyder, Eddie Leavy, Jacob Houston

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Episode 3

Wednesday Morning, 8AM

Mar 21, 201922m8.0 / 10

In the hectic thirty minutes that start every day at Whitlock, Jack tries to retrieve his massage chair from Whitlock's intriguing payroll accountant, Lynette. Durbin and Helen prepare for the morning announcements. Michelle gives a eulogy.

Directed by John SolomonWritten by Michael Patrick O'BrienGuest stars Aparna Brielle, Sari Arambulo, Justin Tinucci, Charlie McCrackin, Elizabeth Alderfer, Jaime Moyer, Allisyn Snyder, Eddie Leavy

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Episode 4

Toledo's Top 100

Mar 28, 201922m9.0 / 10

Jack is aghast to learn he didn't make the Top 10 in Toledo's Top 100 Bachelors, and Durbin did. Victor and Eduardo decide it's time to reveal their feelings to their crushes.

Directed by Maggie CareyWritten by Emily CutlerGuest stars Aparna Brielle, Sari Arambulo, Tania Gunadi, Tiago Roberts, Sam Lazarus, Arthur Keng, Elizabeth Alderfer, Allisyn Snyder

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Episode 5

J'Accuse

Apr 4, 201922m8.0 / 10

Jack uses Michelle's annual murder mystery party to impress Lynette. Meanwhile, in a moment of desperation, the students break into Whitlock High to steal the A.P. Bio practice exams.

Directed by Andrew DeYoungWritten by Michael Patrick O'Brien, Charlie McCrackinGuest stars Aparna Brielle, Sari Arambulo, Ben Seeder, April Adams, John Ponzio, Charlie McCrackin, Yuyao Deng, Elizabeth Alderfer

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Episode 6

Melvin

Apr 11, 201922m8.0 / 10

Jack's war with his neighbor reaches a turning point when it threatens to ruin a date with Lynette. When the school photographer ups his rate, Durbin takes school pictures into his own hands.

Directed by Katie Locke O'BrienWritten by Dan KleinGuest stars Aparna Brielle, Sari Arambulo, Jamila Webb, Alfred Adderly, Christopher Lloyd, Elizabeth Alderfer, Jaime Moyer, Allisyn Snyder

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Episode 7

Personal Everest

Apr 18, 201922m9.0 / 10

Jack is outraged when his old high school bully is hired as a motivational speaker at Whitlock. Mary, Stef and Michelle set their own personal goals of female empowerment, unintentionally causing a rift between Helen and Durbin.

Directed by Payman Benz, Andrew DeYoungWritten by Shelly GossmanGuest stars Aparna Brielle, Sari Arambulo, Tim Heidecker, Charlie McCrackin, Allisyn Snyder, Eddie Leavy, Jacob Houston, Spence Moore II

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Episode 8

Sweet Low Road

Apr 25, 201922m8.0 / 10

When budget cuts threaten to gut Whitlock and put his job in jeopardy, Jack recruits Mary, Stef, and Michelle to take down the Superintendent. Durbin plans an appeal to the heart, while the students plan an appeal to the soul.

Directed by Richie KeenWritten by Donick Cary, Emily CutlerGuest stars Aparna Brielle, Sari Arambulo, Patricia Belcher, Elizabeth Alderfer, Allisyn Snyder, Eddie Leavy, Jacob Houston, Spence Moore II

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Episode 9

Dr. Whoopsie

May 2, 201922m8.0 / 10

After an embarrassing video of him falling off a stage goes viral, Jack plans a viral video of his own. Durbin, Helen and the teachers track down Whitlock's most notorious litterer: The Sugar Daddy.

Directed by Blake McClureWritten by Michael Patrick O'Brien, Rob KleinGuest stars Aparna Brielle, Sari Arambulo, James William O'Halloran, Danielle Demski, Sam Valentine, Aiesha Eser, Elizabeth Alderfer, Allisyn Snyder

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Episode 10

Handcuffed

May 30, 201922m9.5 / 10

When he's kicked off his Harvard phone plan, Jack is offered a chance to leapfrog onto Mary's on one condition: He helps her break up with her scuzzy boyfriend. Meanwhile, Anthony becomes Durbin's right-hand man.

Directed by Jennifer ArnoldWritten by Paula PellGuest stars Aparna Brielle, Sari Arambulo, Brooks Wheelan, David Gborie, Charlie McCrackin, Yuyao Deng, Elizabeth Alderfer, Jaime Moyer

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Episode 11

Spectacle

May 30, 201922m8.0 / 10

After his computer breaks, Jack rallies his class to win the annual Whitlock's Got Talent competition so the prize money can go towards a new laptop. Helen and Durbin put on their best tuxes to host while Mary, Stef and Michelle prepare a hand-bell routine.

Directed by Carrie BrownsteinWritten by Amy HubbsGuest stars Aparna Brielle, Sari Arambulo, Charlie McCrackin, Allisyn Snyder, Eddie Leavy, Jacob Houston, Spence Moore II, Nick Peine

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Episode 12

Ride the Ram

Jun 13, 201922m9.0 / 10

It's the most exciting time of the year at Whitlock: Durbin's birthday and Spirit Week. Jack does his best to steer clear of any school spirit as everyone else comes together to take down their hated rivals at Prairie High.

Directed by Michael Patrick O'BrienWritten by Michael Patrick O'Brien, John SolomonGuest stars Aparna Brielle, Sari Arambulo, Ronnie Alvarez, Jill Basey, Charlie McCrackin, Ian Alda, Freedom Bridgewater, Michelle Kim McCoy

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Episode 13

Kinda Sorta

Jun 13, 201922m8.0 / 10Finale

The college fair comes to Whitlock, and Sarika has an offer to Jack: Get her into Harvard, and she’ll get his book into the hands of her publisher aunt. Meanwhile, Stef prepares for a visit from a fling, Helen applies to college, and Durbin tries to cement his legacy. Season finale.

Directed by Trent O'DonnellWritten by Britt Matt, Shelly GossmanGuest stars Aparna Brielle, Sari Arambulo, Ayden Mayeri, Yuyao Deng, Max Silvestri, Aiesha Eser, Zylan Brooks, Phil Miler

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Episode information updated Jul 22, 2026

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