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As Meredith and Derek begin to find that their "happily ever after" is anything but easy, Cristina develops a crush on a military doctor who brings in a trauma patient. Meanwhile, the Chief and his staff cope with the news that Seattle Grace is no longer considered a top-tier teaching hospital.
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Directed by Rob CornWritten by Shonda RhimesGuest stars Brooke Smith, Mark Saul, Cliff DeYoung, Lauren Stamile, Mariette Hartley, John Getz, Bernadette Peters, Kathy Baker
Alex is offended when Izzie talks about how great a man Alex is to Meredith. Derek is stabbed with the scalpel in the palm of his hand by Rose, while the Chief is stunned over Mercy West's increase in the number of patients, a deadly ice storm ravages Seattle.
Episode credits
Directed by Rob CornWritten by Shonda RhimesGuest stars Brooke Smith, Mark Saul, Cliff DeYoung, Lauren Stamile, Mariette Hartley, John Getz, Bernadette Peters, Kathy Baker
When the plumbing springs a leak, chaos breaks out at Seattle Grace as the Chief tries to put in place new teaching methods. Meanwhile, George takes his residency exam; and Derek attempts to get Meredith's roommates to move out, much to their surprise.
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Directed by Michael PressmanWritten by Krista VernoffGuest stars Brooke Smith, Gloria Garayua, Mark Saul, Kate Anthony, Amy Madigan, Suzy Nakamura, Daniel J. Travanti, Candice Afia
Meredith is sent into a state of panic when Derek finds her mother's diary in the house. Meanwhile, Callie stresses while preparing for her first date with Erica. Later, Cristina stumbles across a part of the hospital no one has ever seen before.
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Directed by Eric StoltzWritten by Debora CahnGuest stars Brooke Smith, Steven W. Bailey, Gloria Garayua, Mark Saul, Amy Aquino, Bre Blair, Max Burkholder, Candice Afia
Bailey heads up a "domino procedure" in which each surgery hinges on the one preceding it. Meanwhile, Derek gets sole credit for the brain-tumor study he did with Meredith; Lexie tries to get George to notice her romantically; and Sloan counsels a desperate Callie in the ways of love.
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Directed by Randall ZiskWritten by Jenna BansGuest stars Brooke Smith, Steven W. Bailey, Gloria Garayua, Mark Saul, Carl Lumbly, George Newbern, Saige Thompson, Colleen Flynn
The chief gives Bailey new power and responsibility. He also gives her a very difficult surgical assignment: remove a girl's inoperable tumor. Meanwhile, new trauma chief Owen (Kevin McKidd) challenges the attendings' methods and the residents' skills.
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Directed by James FrawleyWritten by Mark WildingGuest stars Brooke Smith, Scott Haven, Gloria Garayua, Mark Saul, Adair Tishler, Candice Afia, Brooke Blanchard, Molly Kidder
When the Chief makes an announcement that a solo surgery is up as an award, the residents are sent into a frenzy all trying to get an edge over one another. Meanwhile, Derek asks Bailey for advice after Cristina continues to interfere in his relationship with Meredith. Elsewhere, Erica uncovers a shocking connection between a resident and a patient.
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Directed by Joanna KernsWritten by William HarperGuest stars Brooke Smith, Gloria Garayua, Mark Saul, Jeffrey Dean Morgan, Brandon Scott, Shi Ne Nielson, Tom Verica, Bonnie Bartlett
One of Meredith's oldest friends, Sadie, becomes an intern at Seattle Grace, but Mer's friends are less-than-welcoming to her.
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Directed by Eric StoltzWritten by Stacy McKeeGuest stars Gloria Garayua, Mark Saul, August Schellenberg, Jeffrey Dean Morgan, Ed Lauter, Melissa George, Mary McDonnell, Nicole Cummins-Rubio
Meredith, Cristina and Bailey come to Lexie and Sadie's rescue when a routine surgery goes horribly wrong, as Owen and Derek treat a man seriously injured while sleepwalking and Mark comforts the sleepwalker's distraught daughter.
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Directed by Tom VericaWritten by Joan RaterGuest stars Gloria Garayua, Mark Saul, Jeffrey Dean Morgan, Leslie Grossman, Madeline Carroll, Joshua Malina, John Allen Nelson, Melissa George
Cristina is awarded the first solo surgery among the residents, but she is forced to give it up and choose her replacement; Lexie is impressed when Mark performs a cutting-edge procedure; Callie doesn't know if Sadie is friendly or flirtatious.
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Directed by Arlene SanfordWritten by Peter NowalkGuest stars Gloria Garayua, Mark Saul, Jeffrey Dean Morgan, Christa B. Allen, Kay Panabaker, Rosalind Chao, Melissa George, Mary McDonnell
Bailey teams with Seattle Grace's new pediatric surgeon, Dr. Arizona Robbins, to save the life of a young patient near and dear to her heart, as the admittance of a death row inmate at the hospital stirs anger in Derek and further erodes Meredith and Cristina's friendship; meanwhile, Callie and Sloan work as a team to fight their respective attractions to Sadie and Lexie, and Izzie tells Alex that she's seeing Denny.
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Directed by Rob CornWritten by Debora CahnGuest stars Jessica Capshaw, Steven W. Bailey, Robin Pearson Rose, Gloria Garayua, Candice Afia, Jeffrey Dean Morgan, Melissa George, Perrey Reeves
Derek's mother, Carolyn, makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conceal his relationship with Lexie from her as well; meanwhile, death row inmate William wishes to donate his organs to Bailey and Arizona's patient, as Owen and Cristina try to go on their first date.
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Directed by Jeannot SzwarcWritten by Jenna BansGuest stars Jessica Capshaw, Gloria Garayua, Mark Saul, Candice Afia, Jeffrey Dean Morgan, Melissa George, Eric Stoltz, Tyne Daly
Bailey grows desperate as a patient's condition becomes more and more dire. Everyone in the hospital is stepping up to try to find the boy a new organ donor, including Meredith, who considers a death row patient's wish to die before execution. Meanwhile, an injury leaves Mark in a compromising position in the OR and Cristina awkwardly avoids Owen.
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Directed by Allison Liddi-BrownWritten by Mark WildingGuest stars Jessica Capshaw, Gloria Garayua, Moe Irvin, Mark Saul, Candice Afia, Jeffrey Dean Morgan, Melissa George, Eric Stoltz
Now that Derek has the engagement ring, he searches for the perfect way to propose to Meredith, as Lexie demands that Mark go public with their relationship, and Bailey, encouraged by her work on recent cases and by Dr. Dixon, considers a new direction for her medical career.
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Directed by Julie Anne RobinsonWritten by William HarperGuest stars Jessica Capshaw, Mark Saul, Kate Anthony, Peter MacKenzie, Laura Allen, Melissa George, Mary McDonnell, Jennifer Westfeldt
Addison, Naomi and Sam rush the ailing Archer to Seattle Grace and reunite with old friends Derek and Mark to help save his life; meanwhile, Izzie employs her fellow doctors in a medical game designed to help teach the interns, and Owen runs into a significant someone from his past
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Directed by Dan AttiasWritten by Joan Rater, Tony PhelanGuest stars Kate Walsh, Steven W. Bailey, Gloria Garayua, Mark Saul, Kate Anthony, Grant Show, Candice Afia, Laura Allen
Derek's confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown surgeon into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatrics, is appalled by the Chief's less-than-stellar recommendation letter.
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Directed by Randall ZiskWritten by Peter NowalkGuest stars Jessica Capshaw, Kate Walsh, Gloria Garayua, Mark Saul, Faye Dunaway, Louis Giambalvo, Jennifer Westfeldt, Ben Shenkman
Derek decides to quit after learning that more of his patients have died than survived; Izzie's interns make an unsettling discovery about "Patient X."
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Directed by Rob CornWritten by Jenna BansGuest stars Jessica Capshaw, Loretta Devine, Gloria Garayua, Mark Saul, Wendy Hoopes, Erin Cahill, Michael Rady, Candice Afia
After his fellow surgeons try and fail to bring Derek back to work, Meredith must summon the strength to convince him. Meanwhile the hospital is abuzz as Mark attempts a rare face transplant surgery. Cristina, at last awarded her first solo surgery, is more focused on the needs of her friends, and Izzie does her best to keep her medical condition a secret.
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Directed by Jessica YuWritten by Zoanne ClackGuest stars Greta Sesheta, Mark Saul, Candice Afia, Larry Sullivan, Emily Kuroda, Molly Kidder, Brandon Scott, Joe Williamson
All eyes are on Derek as he is set to perform his first surgery after his breakdown; attention is also set on Izzie, whose medical condition requires her to undergo a difficult surgery; and Owen has another PTSD episode that injures Cristina and traumatizes both of them, throwing the future of their relationship into question.
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Directed by Edward OrnelasWritten by Stacy McKeeGuest stars Jessica Capshaw, Gloria Garayua, Mark Saul, Candice Afia, Molly Hagan, Kimberly Elise, Todd Waring, Molly Kidder
As preparations continue for Meredith and Derek's wedding, Izzie receives a surprise hospital visit from her handful-of-a-mother, Robbie. Meanwhile, a newly sober Thatcher visits his daughters, Meredith and Lexie, in order to make amends, and the Chief and Meredith bitterly fight over a controversial medical case.
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Directed by Tom VericaWritten by Krista VernoffGuest stars Jessica Capshaw, Jeff Perry, Kellie Martin, Megan Henning, Nina Siemaszko, Sharon Lawrence, Brooke Blanchard, Destiny Whitlock
As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.
Episode credits
Directed by Rob CornWritten by Shonda RhimesGuest stars Jessica Capshaw, Mac Brandt, Mark Saul, Candice Afia, Jeffrey Dean Morgan, Payton Silver, Molly Kidder, Joe Williamson
In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level and a patient makes Owen reassess his place at Seattle Grace.
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Directed by Bill D'Elia, Rob CornWritten by Allan Heinberg, Debora CahnGuest stars Jessica Capshaw, Zach Gilford, Jeffrey Dean Morgan, Kimberly Elise, Liza Weil, Debra Mooney, Webster Williams, Brock Cuchna
In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie's friends anxiously await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program, and the victim of a near-fatal traffic accident brings the talents of Seattle Grace's doctors together. This is the second hour of a 2-hour season finale.
Episode credits
Directed by Bill D'Elia, Rob CornWritten by Allan Heinberg, Debora CahnGuest stars Jessica Capshaw, Shannon Lucio, Brooke Blanchard, John Cappon
