William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch. He is a brilliant scientist out of touch with his own feelings, and she is a single working mother ahead of her time. The series chronicles their unusual lives, romance, and unlikely pop culture trajectory.
William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch. He is a brilliant scientist out of touch with his own feelings, and she is a single working mother ahead of her time. The series chronicles their unusual lives, romance, and unlikely pop culture trajectory.
Season 1 episodes
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Dr. William Masters, Washington University’s foremost OB/GYN, runs a successful medical practice by day and conducts a secret study of human sexuality by night. Former nightclub singer Virginia Johnson joins the hospital secretarial staff and proves herself to be an asset to Masters’ work.
Episode credits
Directed by John MaddenWritten by Michelle AshfordGuest stars Annaleigh Ashford, Roslyn Ruff, Margo Martindale, Steve Rosen, Johanna Day, Mary Jo McConnell, Jeffrey C. Hawkins, Linda Marie Larson
On the heels of Masters’ proposal that they participate in the sexual response study, Johnson considers the best course of action to keep her job – only to find she no longer has one. The study has been forced out of the hospital and Masters believes Johnson is to blame. As Johnson fights to save her job and struggles to care for her kids, Masters moves his study to a brothel. But Masters soon discovers that the chaos of the cathouse is unmanageable without Johnson’s help.
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Directed by Michael DinnerWritten by Michelle AshfordGuest stars Annaleigh Ashford, Elizabeth Dennehy, April Parker Jones, Ruby Lewis, Kristin Slaysman, Susan-Kate Heaney, Khali Macintyre, Debbie Jaffe
Masters and Johnson continue their research in the brothel but skewed data confirms that Masters must get the study back into the hospital. At the hospital, Johnson is surprised to learn that a distinguished new doctor on the OB/GYN floor is a woman who has no interest in female solidarity. Meanwhile, Libby struggles to conceive and Dr. Ethan Haas gets the case of a lifetime – a woman pregnant with quadruplets.
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Directed by Lawrence TrillingWritten by Sam ShawGuest stars Annaleigh Ashford, Mae Whitman, Lauren Weedman, Nicholle Tom, Sara Rae Foster, Ellen Wroe, Bobby Campo, David Ury
With the study back in the hospital, Masters and Johnson recruit new participants on campus. But Johnson is shocked when her ex-husband George, who’s crashing on her couch, wants to sign up. Masters’ mother comes to visit, but her new take on life stirs up painful memories of his childhood. And Libby’s attempt at playing matchmaker with Virginia and Ethan doesn’t go as smoothly as she’d hoped.
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Directed by Jennifer GetzingerWritten by Amy LippmanGuest stars Michael Mantell, Martha Hackett, Emily Bridges, Dean Chekvala, Kira Sternbach, Gabe O'Mara, Monica Hewes, Michael Tower
When Masters and Johnson expand the study to include couples, they discover that the science of sex is easily complicated by the mystery of attraction. Johnson tries to connect with her son who prefers his dad. In anticipation of his baby’s impending arrival, Masters experiences anxiety about becoming a father. And Dr. Ethan Haas learns that dating the provost’s daughter could impact his medical career.
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Directed by Michael AptedWritten by Michelle Ashford, Sam ShawGuest stars Joseph Lyle Taylor, Kyle Jones, Emily Davenport, Romina Bovolini, Cheryl Bricker, Mike Peebler, Susie Schelling, Shaun Rylee
In the aftermath of the miscarriage, Libby and Masters travel to Miami for some much needed rest and relaxation, but Masters is drawn back into his work by a sexually adventurous couple next door. Alone in the hospital, Virginia enlists Jane in an effort to debunk Freud’s theory that one kind of female orgasm is better than another. And Langham finds an unlikely cure for his sexual dysfunction in Margaret Scully.
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Directed by Adam DavidsonWritten by Lyn Greene, Richard LevineGuest stars Barry Bostwick, Ann Cusack, Caroline Lagerfelt, Leah Costello, Rachel Kimsey, Helen Wilson, Kirsten Kollender, Eileen Grubba
Masters and Johnson continue their sexual response study – now as participants – but Johnson fears their work may be interfering with Masters’ home life. Libby pressures Dr. Haas to resume her fertility treatments in secret. Meanwhile, Haas struggles to let go of feelings for Virginia as his relationship with Vivian deepens. And Margaret Scully, caught in her infidelity, confronts her husband on the mounting problems in their marriage.
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Directed by Tim FywellWritten by Tyler BensingerGuest stars Alan Ruck, John Pollono, Brian R. Norris, Shanna Collins, Micah A. Hauptman, Pepper Binkley, Michael Dunn, Mary Catalano
Masters and Johnson decide that the best way to record their study findings is to film them, but to do so they have to enlist outside help. Johnson redoubles her efforts to get a college degree, only to find that Dr. DePaul’s Basic Anatomy class is a requirement. Meanwhile, Haas and Langham – both unsure in their relationships – convince each other of the merits of being a married man. And after Margaret catches him in a compromising position, Scully takes drastic steps to control his sexual impulses.
Episode credits
Directed by Michael AptedWritten by Michael Cunningham, Tyler BensingerGuest stars Kevin Christy, Finn Wittrock, Flex Alexander, Brit Shaw, Gary Kraus, Braden Moran, Logan Donovan, Adam Silver
When Masters and Johnson decide to film external reactions in the study, they must convince Lester and Jane that their footage won’t cross the line into pornography. Haas and Vivian’s plans for a Presbyterian church wedding are sidetracked when Haas reveals he’s Jewish. Libby keeps her pregnancy a secret from Masters and instead encourages him to mend his relationship with his mother. But during late night visits to the hospital, Estabrooks observes Masters and Johnson’s intimate relationship.
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Directed by Jennifer GetzingerWritten by Noelle ValdiviaGuest stars Kevin Christy, Doug McKeon, Rob Kerkovich, Bennet Guillory, Claire van der Boom, Bug Hall, Gil McKinney, Kate Fuglei
The hospital takes part in a nationwide civil defense drill, and the heightened atmosphere escalates conflicts among the staff. A former study participant reveals she’s pregnant and wants to know the identity of the father. Masters and Johnson, their relationship strained after ending their study participation, butt heads on whether to maintain study confidentiality or take responsibility. Haas learns he’s been denied a future job at the hospital but wrongly assumes his breakup with Vivian is to blame. Margaret Scully seeks answers about her husband’s sexuality from an unlikely source.
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Directed by Lesli Linka GlatterWritten by Sam ShawGuest stars Kevin Christy, Spencer Garrett, Anne Dudek, Joan Severance, Mary Passeri, Betsy Zajko, Molly Hagan, Zak Barnett
With Johnson no longer on his team, Masters accepts Libby’s offer to help compile the study work for a hospital-wide presentation. But when Masters sees another doctor’s presentation put his colleagues to sleep, he becomes determined to grab their attention even if it means pushing through provoking, but incomplete, research. Dr. DePaul and Johnson travel to a medical convention and DePaul opens up on why her work on the Pap smear is so important. And Virginia’s ex-husband George returns to find Ethan Haas playing father to his children.
Episode credits
Directed by Phil AbrahamWritten by Amy LippmanGuest stars Michael Cassidy, Amanda Jane Cooper, Rebecca Staab, Rebecca Larsen, Liv von Oelreich, Patty Cornell, William Charles Mitchell, Cheyenne Wilbur
Masters’ work on human sexuality culminates with a hospital-wide presentation of his and Johnson’s research findings. But when Masters attempts to push the envelope with the external footage of the female orgasm, the doctors’ response to the film is not what he had hoped. Meanwhile, Haas entertains a job offer at UCLA Hospital and considers what a move would mean for his relationship with Virginia. Scully pursues electroshock treatment with the hope of curing his homosexuality but Margaret has second thoughts about the risks involved.
Episode credits
Directed by Michael DinnerWritten by Michelle AshfordGuest stars Kevin Christy, Jason Kravits, James Eckhouse, Robert Joy, Tim Ransom, Linara Washington, Blake Robbins, Jocelyn Ayanna
