TV series
Solve the puzzle. Save the patient.
A year after the death of his friend and partner Sherlock Holmes at the hands of Moriarty, Dr. John Watson resumes his medical career as the head of a clinic dedicated to treating rare disorders. However, he soon finds that his old life is not done with him yet.
Availability
Watson premiered January 26, 2025. We don't have a confirmed streaming, rental or purchase option yet.
A year after the death of his friend and partner Sherlock Holmes at the hands of Moriarty, Dr. John Watson resumes his medical career as the head of a clinic dedicated to treating rare disorders. However, he soon finds that his old life is not done with him yet.
Choose an episode, then use the watch options above for the show.
Episode 1
Watson and the fellows spring back into action when Mary’s mother accidentally poisons herself while suffering from a rare form of dementia that is progressing with impossible speed. Meanwhile, Sherlock Holmes resurfaces after being presumed dead.
Directed by Larry TengWritten by Craig Sweeny, Sharon MoalemGuest stars Riley Orr, Tika Sumpter, Juanita Jennings, Khary Payton, John Cassini, Robert Carlyle, Rryla McIntosh, Shalyn Ferdinand
Episode 2
A microbiology researcher returns from an expedition to Siberia, leading to a possible outbreak of a revived pathogen. Watson reconnects with Sherlock Holmes.
Directed by Tara Nicole WeyrWritten by Michael NarducciGuest stars Riley Orr, John Cassini, Robert Carlyle, Kerry O'Malley, Tzi Ma, Craig March, Max Montesi, Bahareh Yaraghi
Episode 3
Watson and the team work alongside Laila to help a patient named Maxine, a 30-year-old who looks 10 years old.
Directed by Larry TengWritten by Elizabeth J.B. KlaviterGuest stars Louriza Tronco, Tika Sumpter, John Cassini, Ava Anton, Noah Mills, Riley Orr, Robert Underwood, Genevieve Fleming
Episode 4
Watson and the team jump into action when four new patients are brought to UHOP with wounds that appear to be infected with a flesh-eating bacterium following a tornado. Meanwhile, Shinwell searches for meaning as a nursing student and Adam’s wedding to Lauren risks being halted.
Directed by Sheelin ChokseyWritten by Charly Evon SimpsonGuest stars Riley Orr, Amanda Crew, Kalyn Miles, Margot Bingham, Derek Wilson, Anja Savcic, Seyi Balogun, Troy Mclaughlin
Episode 5
While visiting another hospital, Watson becomes convinced that a coma patient is suffering from locked-in syndrome and has been mistaken for a coma patient for over a decade. After the patient is transferred to UHOP for treatment, he shocks the team with chilling messages. Meanwhile, Sherlock is back in town and is staying with Watson.
Directed by Guy FerlandWritten by Craig Sweeny, Teresa TuanGuest stars Vincent Gale, Rachel Hayward, John Cassini, Robert Carlyle, Noah Mills, Rebecca Field, Dean Paul Gibson, Alisha Ahamed
Episode 6
Watson and the fellows race against time to save the life of Xavier, a 21-year-old athlete with a fast-growing, seemingly incurable cancer. Meanwhile, Mycroft Holmes lets Watson know his team’s work at UHOP may no longer have funding available.
Directed by Clara AranovichWritten by Anna MackeyGuest stars Riley Orr, Vincent Gale, Johnno Wilson, Chris Gray, Carlena Britch, Jamall Johnson, Maggie Ma, Cindy Piper
Episode 7
Watson's father, Hamish, visits UHOP to introduce Watson and the fellows to his protégé, Annabelle, a saxophone prodigy with musically induced blackouts. As Annabelle's condition worsens, Watson must confront his long-standing tensions with his father in order to save her.
Directed by Amanda RowWritten by Teresa TuanGuest stars Riley Orr, Tzi Ma, Clarke Peters, Piper Curda, Shane Dean, Benjamin Hart Hinds, Alexander Boynton, Michael Connor
Episode 8
UHOP veers into terror when Watson and the fellows are taken hostage by a man with a bomb strapped to his chest who is desperate to find a cure for his 9-year-old daughter’s illness.
Directed by Larry TengWritten by Charly Evon Simpson, Michael Narducci, Jeffrey Paul KingGuest stars Riley Orr, John Cassini, Noah Mills, Jon Beavers, Lucy Turnbull, Chris Pereira, Anthony Scardera, Greg Zach
Episode 9
Watson and the fellows help Laila’s son Micah – who was injured in a car accident while pursuing his crush, Bex, with the help of his AI chatbot.
Directed by Jennifer LynchWritten by Craig Sweeny, Shardé Miller, Jason InmanGuest stars Riley Orr, Louriza Tronco, Tika Sumpter, John Cassini, Margot Bingham, Shannon Purser, Chase W. Dillon, Juliette Hawk
Episode 10
Watson’s biohacker friend Hobie returns when he rushes his new girlfriend to the Holmes Clinic after they partake in a gene-editing experiment that goes wrong. Meanwhile, Watson becomes suspicious of Sherlock.
Directed by Anton CropperWritten by Adam Samuel Goldman, Heather RossGuest stars Riley Orr, Kareem Malcolm, Nat Faxon, Rachel Hayward, Robert Carlyle, Noah Mills, Jessica Miesel, Jessie Fraser
Episode 11
Watson and the fellows race against the clock to save a man and his pregnant wife from a terrifying sinkhole. Meanwhile, Ingrid’s future with her therapy group becomes unclear.
Directed by Sheelin ChokseyWritten by Jason InmanGuest stars Riley Orr, John Cassini, Noah Mills, Марго Бингхэм, Landon Liboiron, Madeline Zima, Alexandra Khan-Anselmo, Regan Ross
Episode 12
When a patient arrives at the Holmes Clinic plagued by a mysterious neurological disorder, Watson and the fellows discover they were forced to eat their parents amid a childhood survival incident. Meanwhile, Adam is struggling with how his future will change as a father.
Directed by Ruben GarciaWritten by Anna Mackey, Michael Narducci, Jeffrey Paul KingGuest stars Riley Orr, Amanda Crew, Dani Alvarado, Ashton Moio, Gavin Langelo, Hannah Henney, Victoria Skye Sealy, Madeleine White
Episode 13
Watson and the fellows fight to revive a 30-year-old woman, Audrey, after her heart inexplicably stops repeatedly until they discover she has a rare phenomenon called Lazarus syndrome. As these revivals continue, she uses the short window of time available to right her greatest wrong.
Directed by Larry TengWritten by Bashir GavrielGuest stars Riley Orr, Karen Robinson, Tika Sumpter, C.J. Lindsey, Tori Anderson, Dave Davis, Arthur McAlpine III, Kathleen Duborg
Episode 14
Watson is sued for Wrongful Life by a long-term patient suffering from VACTERL association, after undergoing multiple painful surgeries.
Directed by Jeffrey W. ByrdWritten by Charly Evon Simpson, Elizabeth J.B. KlaviterGuest stars Riley Orr, Alexandria Maillot, April Parker Jones, Michelle Veintimilla, Thamela Mpumlwana, Paul du Toit, Theresa Wong, Aleksandra Koel
Episode 15
Watson and the fellows race to save the life of a young woman who needs a lifesaving kidney donation. Meanwhile, Sherlock returns to help crack unsolved cases in Pittsburgh.
Directed by Valerie WeissWritten by Charly Evon SimpsonGuest stars Riley Orr, Rachel Hayward, Robert Carlyle, Patrick Fabian, Nadia Alexander, Alex Rose, Mia Golden, Zoë Christie
Episode 16
Watson investigates a case involving a mentally unstable mother, with the woman's delusions serving as a mirror to his own newly discovered hallucinations.
Directed by Loren YaconelliWritten by Shardé Miller, Anna MackeyGuest stars Riley Orr, Karen Robinson, Rachel Hayward, Tika Sumpter, Robert Carlyle, Noah Mills, Anna Wood, Annabelle Toomey
Episode 17
In the wake of the car accident, Watson and Laila lie injured and awaiting rescue as the team races to find them before it’s too late. Meanwhile, in a state between life and death, Watson’s mind plays out a modern-day investigation of a case that has long haunted him.
Directed by Larry TengWritten by Adam Pasen, Samuel Evan HorowitzGuest stars Riley Orr, Karen Robinson, Louriza Tronco, Amanda Crew, Tika Sumpter, Robert Carlyle, Helen Cespedes, Chris McGarry
Episode 18
Following his brain tumor diagnosis, Watson goes on medical leave to seek treatment, leaving Mary in charge of The Holmes Clinic as a notorious South American dictator demands Watson see to his mysterious autoimmune condition personally. Meanwhile, Ingrid grows more concerned about Beck’s obsession with Sasha.
Directed by Clara AranovichWritten by Michael NarducciGuest stars Riley Orr, Karen Robinson, Rachel Hayward, Noah Mills, Marco Grazzini, Paul Moniz de Sa, Alana Hawley Purvis, Julio Rod Marin
Episode 19
As Adam's wife goes in for a C-section to deliver triplets, chaos ensues when their OB-GYN passes out in the operating room. Meanwhile, a severe storm detours Watson and Mary's trip to find a renowned doctor to remove Watson's brain tumor.
Directed by Jennifer LynchWritten by Teresa TuanGuest stars Riley Orr, Amanda Crew, Rachel Hayward, Robert Carlyle, Марго Бингхэм, Jonathan R. Freeman, Helen Cespedes, Alessandro Juliani
Episode 20
A seemingly random murder outside of UHOP sets the stage for the arrival of someone from Watson and Sherlock Holmes' past.
Directed by Larry TengWritten by Sharon Moalem, Rebecca HofherrGuest stars Hampton Fluker, Karen Robinson, Rachel Hayward, John Cassini, Robert Carlyle, Riley Orr, Марго Бингхэм, Suzy Eddie Izzard
Episode information updated Sep 20, 2026
Available now in United States
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CBSUnited States
CBS StudiosUnited States
Kapital EntertainmentUnited States
